Influenza A(H1N2) variant virus – Outbreak

Author: Ramsha Zafar (MBBS) | Proofread: Muhammad Rehan Mian (MSPH) | Reviewed:  Muhammad Rehan Mian (MSPH) | July 17, 2020

On 12th April 2020 a 22-year-old female, who worked at a swine slaughterhouse in South Brazil, developed an influenza-like illness. She sought medical care two days later and has now recovered.

A real-time RT-PCR test identified a non-sub typable influenza A virus. On 22nd June, genetic sequencing characterized this virus as an influenza A(H1N2)v virus. Further genetic and phenotypic characterization of the virus from the patient is ongoing.

A preliminary investigation revealed that a second worker of the slaughterhouse also developed respiratory symptoms during the same timeframe as the confirmed case, but no sample was collected from this person. No other suspected cases amongst contacts of the confirmed case have been identified.

Since 2005, 26 cases of influenza A(H1N2)v have been reported to the WHO, including two from Brazil. Most cases have presented with mild illness, and there has been no evidence of person-to-person transmission.

Swine influenza viruses of different genetic characteristics circulate in swine populations in many regions of the world. Most human cases are the result of exposure to these viruses through contact with infected swine or contaminated environments. Because these viruses continue to be detected in swine populations around the world, further human cases can be expected.

Source: World Health Organization (WHO)

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